Cell adhesion molecules of the immunoglobulin superfamily found in the central nervous system of insects. Involved with fasciculation of axons and probably in pathfinding during morphogenesis of the nervous system. The sequence of fasciclin II shows that it shares structural motifs with a variety of vertebrate CAMs, See contactin, F11, neurofascin, TAG-1, Drosophila neuroglian.

Dictionary of molecular biology. 2004.

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  • fasciculation — Tendency of developing neurites to grow along exisiting neurites and hence form bundles or fascicles. Selective fasciculation in developing vertebrate nervous systems is thought to involve the axon associated cell adhesion molecules L1, F11,… …   Dictionary of molecular biology

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